Analysis of David Foster Wallace´s Novel Infinite Jest

Self and other The theme of self versus other evident in the novel is reflective of the postmodern idea that there exist boundaries between the two separate entities, the internal and external, perception and reality. This theme manifests as the idea that the ‘other’ can influence the ‘self’, that society controls the individual. Wallace also explores the theme of self and other in Infinite Jest by contrasting the boundary between what goes on inside the characters’ heads and the outside world. Characters such as Millicent Kent feel a sense of loneliness in their own thoughts and consequently seek diversion in something other. Kent alludes to the â€Å"Taoist paraboloid logo† (Wallace 265) which symbolizes self and other when she â€Å"asked Mario if he’d ever seen a girl’s yin-yang before† (Wallace 124). Kent draws a parallel between the two pairs of seemingly opposite forces that are actually connected to and dependent up on each other. For Millicent and Mario, yin and yang symbolize female and male, but also a balanced relationship that leads the characters out of loneliness. Through his allusion to ideological jargon, Wallace suggests that a harmonious balance between self and other is necessary. Irony leads to addiction One of the most poignant instances of irony is in regards to the cynicism in postmodern society. The characters Infinite Jest are remarkably sarcastic and the narration of the novel has a dark, satirical quality to it. David Foster Wallace uses Remy

Prevention of Leukemic Stem Cells Developing from...

PROJECT TITLE: Prevention of Leukemic Stem Cells developing from Hematopoietic Stem Cells by targeting the Ras/Raf/MEK/ERK pathways INVESTIGATOR: Michelle Nguyen (Spring 2014) PROJECT SUMMARY: According to the study done in 2014 by the National Cancer Institute, leukemia is the 11th most common type of cancer (Howlader et al., 2011). This cancer that originate in the bone marrow or other tissues that form blood cells causing them to divide rapidly without any control (Wu, 2012). These leukemia stem cells are derived from hematopoietic stem cells but because of high telomerase activity, the stem cells have the ability to self-renew limitlessly (Heidel, Mar, Armstrong, 2011). As of right now, there are many treatments available such as†¦show more content†¦To confirm the efficiency of the drug, the drugs will administered to NOD/SCID mice with leukemic properties and effects will be monitored. RELEVANCE: The most common form of the blood cancer is the production of white blood cells. This buildup of these white blood cells hinders the body from control bleeding, supplying oxygen to the tissues, removing waste from tissues, and to fight infections. Approximately, someone in the US dies from a blood cancer every ten minutes. Of the blood cancers, leukemia accounts for 33% of the deaths (Siegel, Naishadham, Jemal, 2013). Because the cancer stems from a transformation from healthy hematopoietic stem cells to leukemic stem cells, it would be beneficial to treat the disease with a stem cell therapy. The purpose of this study is to understand the mechanism of how hematopoietic stem cells are turned into leukemia stem cells and be able to prevent the transformation. It will be another step for researchers to find a less invasive method of threating leukemia that is safe for all ages and severity. The understanding of which factors induce the conversion of how HSCs to LSCs and bei ng able to prevent it opens doors to new therapies and treatments and make stem cell transplants more safe and widely available. RESEARCH PLAN: Hypothesis: By understanding the pathways that dictate the mechanism that causes a hematopoietic stem cell to mutate into a leukemic stem cell, an inhibitor/antagonist

After Reconstruction Essay Example For Students

After Reconstruction Essay After the Reconstruction There were several factors that lead to the Northern Republicans abandoning Reconstruction. Some of the factors were due to an increase of racial violence, an economic depression, and the corruption of the Republican government. Racial violence was a key factor due to Southern Democrats resorting in trying to intimidate by abuse of the African Americans and also poor whites. It started because of military occupation in the South. A big part of the violence was because of lynching and the Ku Klux Klan. Lynching was not at all rare in the South and an example is of the grocery competitors in the story Anti-Lynching Campaign in Tennessee. Even the judge of Memphis said to the sheriff to take a hundred men, go out to the Curve at once, and shoot down on sight any Negro who appears to be making trouble just because they wanted to vent their feelings amongst themselves with no evidence portrayed whatsoever.(AF 57) As if lynchings were not bad enough a group known as the KKK began to strike. They were terrorists who were dedicated to winning back the South for the Democrats. In the story of The Murder of Jim Williams, an innocent black man was killed because he was thought to be part of a militia and have guns.(AF 2-12) It is sad to think that his wife even had to watch him being taken away and not able to do or call upon for help from anyone. The government then attacked such groups as the KKK with acts passed by congress in 1872, that gave the okay to prosecute against those who prevented blacks from voting. The economic depression was in the North do to tons of business failures and such a high unemployment rate at the time. Each cycle of economic depression was caused by the railroads in someway. And lastly, the reason of the corruption of Republican government. The Republicans believed that congress was infested with corruption within the senate and legislature. Some of which even allowed for such things as the black codes, and not allowing African Americans to vote because the were illiterate. Reconstruction came across as a failure for the most part, but had nothing but good intentions in mind. Along with some of the failures were the black codes. Black codes were laws that restricted freed slaves from exercising their Constitutional rights. This had the effect of making blacks second-class citizens. If you believe that all people are equal, then you would have to agree that the black codes were a bad thing. Black codes kept blacks from gathering together, set curfews on when they could be out, restricted their travel, and many other things. The black codes alone did not make Reconstruction a failure. The primary reason Reconstruction failed was that the Federal government simply lost interest in it by the mid-1770s and allowed the South to go back to almost the way it was before the Civil War, with the exception that slavery was no longer legal. It was also a very corrupt and difficult time in our nations history. When the Civil War ended many of the policies that Lincoln had started were continued by President Johnson. Lincoln had issued the Emancipation Proclamation that went into effect on January 1, 1863. This only freed the slaves in those states in rebellion against the United States. With this initiated and the South losing the war, it was only natural for these ideas to continue. In 1865 was the Thirteenth Amendment which freed all slaves and caused a major invasion of people trying to earn a living for themselves. The only way most of them could support themselves and their families was to continue in the jobs they held as slaves. This meant many of them needed land for crops, creating a perfect opportunity for many whites and some blacks to make huge profits selling land or having the former slaves sharecrop. In many cases even though free men, the former slaves were not much better off than before. President Johnson felt obligated to continue Lincolns views and policies on freeing the slaves. .u72e48b83d74d0be81d3ad10cb410caab , .u72e48b83d74d0be81d3ad10cb410caab .postImageUrl , .u72e48b83d74d0be81d3ad10cb410caab .centered-text-area { min-height: 80px; position: relative; } .u72e48b83d74d0be81d3ad10cb410caab , .u72e48b83d74d0be81d3ad10cb410caab:hover , .u72e48b83d74d0be81d3ad10cb410caab:visited , .u72e48b83d74d0be81d3ad10cb410caab:active { border:0!important; } .u72e48b83d74d0be81d3ad10cb410caab .clearfix:after { content: ""; display: table; clear: both; } .u72e48b83d74d0be81d3ad10cb410caab { display: block; transition: background-color 250ms; webkit-transition: background-color 250ms; width: 100%; opacity: 1; transition: opacity 250ms; webkit-transition: opacity 250ms; background-color: #95A5A6; } .u72e48b83d74d0be81d3ad10cb410caab:active , .u72e48b83d74d0be81d3ad10cb410caab:hover { opacity: 1; transition: opacity 250ms; webkit-transition: opacity 250ms; background-color: #2C3E50; } .u72e48b83d74d0be81d3ad10cb410caab .centered-text-area { width: 100%; position: relative ; } .u72e48b83d74d0be81d3ad10cb410caab .ctaText { border-bottom: 0 solid #fff; color: #2980B9; font-size: 16px; font-weight: bold; margin: 0; padding: 0; text-decoration: underline; } .u72e48b83d74d0be81d3ad10cb410caab .postTitle { color: #FFFFFF; font-size: 16px; font-weight: 600; margin: 0; padding: 0; width: 100%; } .u72e48b83d74d0be81d3ad10cb410caab .ctaButton { background-color: #7F8C8D!important; color: #2980B9; border: none; border-radius: 3px; box-shadow: none; font-size: 14px; font-weight: bold; line-height: 26px; moz-border-radius: 3px; text-align: center; text-decoration: none; text-shadow: none; width: 80px; min-height: 80px; background: url(https://artscolumbia.org/wp-content/plugins/intelly-related-posts/assets/images/simple-arrow.png)no-repeat; position: absolute; right: 0; top: 0; } .u72e48b83d74d0be81d3ad10cb410caab:hover .ctaButton { background-color: #34495E!important; } .u72e48b83d74d0be81d3ad10cb410caab .centered-text { display: table; height: 80px; padding-left : 18px; top: 0; } .u72e48b83d74d0be81d3ad10cb410caab .u72e48b83d74d0be81d3ad10cb410caab-content { display: table-cell; margin: 0; padding: 0; padding-right: 108px; position: relative; vertical-align: middle; width: 100%; } .u72e48b83d74d0be81d3ad10cb410caab:after { content: ""; display: block; clear: both; } READ: Liberal Arts Education Essay Paper He went against strong opposition from Congress in passing the various .